CLASP1 Polyclonal Antibody-BS62340

CLASP1 Polyclonal Antibody

Catalogue Numbers: BS62340-50, BS62340-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q7Z460

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB:1:500~1:1000 IHC:1:50~1:200

Background: Members of the CLASP family, including CLASP1, are mammalian microtubule plus-end binding proteins that interact with CLIPs in order to stabilize the microtubule structures in transfected cells. CLASP1 localizes near the distal end of growing spindle microtubules during mitosis and is a component of the outer corona region of kinetochores. CLASP proteins stabilize microtubules by promoting pauses and restricting MT growth. Defects in CLASP1 cause collapse of the spindle, attachment of kinetochores to short microtubules, and other abnormal mitotic behaviors.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CLASP1 polyclonal antibody detects endogenous levels of CLASP1 protein.

Extra Notes: Western blot (WB) analysis of CLASP1 polyclonal antibody at 1:500 dilution
LaneA:PC12 whole cell lysate
LaneB:AML-12 whole cell lysate
LaneC:HEK293T whole cell lysate
LaneD:L02 whole cell lysate
LaneE:A549 whole cell lysate

Bioworld Molecular Weight: ~ 169 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: CLIP-associating protein 1; Cytoplasmic linker-associated protein 1; Multiple asters homolog 1; Protein Orbit homolog 1; hOrbit1; CLASP1; KIAA0622, MAST1

Immunogen: Synthetic peptide, corresponding to Human CLASP1.

Conjugate: Unconjugated

Modification: Unmodified