Claudin-10 rabbit pAb - ES7948

Claudin-10 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7948-50, ES7948-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.[provided by RefSeq, Jun 2010],

Alternate Name: CLDN10; Claudin-10; OSP-like protein

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human Claudin 10. AA range:179-228

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 25kD

Human Gene ID: 9071

Human SWISS Prot NO: P78369

Subcellular Location: Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.

Research Use Only