Claudin-19 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA23425-50, RA23425-100
Citations, Manuals and MSDS Available upon request.
Background: claudin 19 (CLDN19) Homo sapiens The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO) . HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Alternative Names: CLDN19; Claudin-19
Applications: WB; ELISA
Species Cross-Reactivity: Human; Rat
GeneID (Human): 149461
Protein MW (KDa): 23
SWISS: Q8N6F1
Source: Rabbit
Research Use Only