Product Description

Claudin-19 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA23425-50, RA23425-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: claudin 19 (CLDN19) Homo sapiens The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010],

Reactivity: Human, Rat

Host: Rabbit

Applications: WB, ELISA

Alternate Names: CLDN19, Claudin-19

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight: 23

Protein Molecular Weight (kDa): 23

Storage: -20°C/1 year

Human Gene ID: 149461

Human SwissProt Number: Q8N6F1

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only