Claudin-5 (phospho Tyr217) rabbit pAb - ES7400

Claudin-5 (phospho Tyr217) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7400-50, ES7400-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2008],

Alternate Name: CLDN5; AWAL; TMVCF; Claudin-5; Transmembrane protein deleted in VCFS; TMDVCF

Source: Rabbit

Applications: IHC; IF; WB; ELISA

Dilution: WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human Claudin 5 around the phosphorylation site of Tyr217. AA range:169-218

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 23kD

Human Gene ID: 7122

Human SWISS Prot NO: O00501

Subcellular Location: Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.

Research Use Only