CLC-7 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA23443-50, RA23443-100
Citations, Manuals and MSDS Available upon request.
Background: chloride voltage-gated channel 7 (CLCN7) Homo sapiens The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood. [provided by RefSeq, Jul 2008],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Alternative Names: CLCN7; H (+) /Cl (-) exchange transporter 7; Chloride channel 7 alpha subunit; Chloride channel protein 7; ClC-7
Applications: WB; ELISA
Species Cross-Reactivity: Human; Mouse; Rat
GeneID (Human): 1186
Protein MW (KDa): 90
SWISS: P51798
Source: Rabbit
Research Use Only