CLC-7 rabbit pAb - ES1993

CLC-7 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES1993-50, ES1993-100

Citations, Manuals and MSDS Available upon request.

Background: chloride voltage-gated channel 7 (CLCN7) Homo sapiens The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood. [provided by RefSeq, Jul 2008],

Alternate Name: CLCN7; H (+)/Cl (-) exchange transporter 7; Chloride channel 7 alpha subunit; Chloride channel protein 7; ClC-7

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human CLCN7. AA range:10-59

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 90kD

Human Gene ID: 1186

Human SWISS Prot NO: P51798

Subcellular Location: Lysosome membrane; Multi-pass membrane protein.

Research Use Only