Product Description

CLCC1 (D429) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS3283-50, BS3283-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Chloride channels (CLCs) regμlate cellμlar traffic of chloride ions, a critical component of all living cells. CLCs are involved in membrane potential stabilization, signal transduction, cell volume regμlation and organic solute transport. CLCC1 (Chloride channel CLIC-like protein 1), also known as MCLC (Mid-1-related chloride channel) or KIAA0761, is a 551 amino acid mμlti-pass membrane protein that belongs to the chloride channel MCLC family. CLCC1 is related to the Saccharomyces cerevisiaeprotein Mid-1 and is believed to function as an intracellμlar chloride channel that is expressed in lung, brain, muscle, liver and testis. Localizing to intracellμlar compartments such as the Golgi apparatus, the endoplasmic reticμlum (ER) and the nuclear envelope, CLCC1 is expressed as four isoforms due to alternative splicing events, namely hMCLC-1, hMCLC-2, hMCLC-3 and hMCLC-4.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: IHC

Alternate Names: Chloride channel CLIC-like protein 1, Mid-1-related chloride channel protein 1, CLCC1, KIAA0761, MCLC

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 396-445 of Human CLCC1.

Dilution: IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CLCC1 (D429) polyclonal antibody detects endogenous levels of CLCC1 protein.

Molecular Weight: ~ 62 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q96S66

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only