CLCN1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A5739-20, A5739-100
Citations, Manuals and MSDS Available upon request.
Background: The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen) . Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 109kDa
Observed Molecular Weight: 109kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 1180
SWISS: P35523
Alternate Names: CLC1; CLCN1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Endocrine Metabolism, Neuroscience.
NCBI Alias: CLCN1
Research Use Only