Product Description

CLCN7 Polyclonal Antibody

Catalogue Numbers: BS67572-50, BS67572-100

Sizes: 50µl, 100µl

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: P51798

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: Slowly voltage-gated channel mediating the exchange of chloride ions against protons.Functions as antiporter and contributes to the acidification of the lysosome lumen and may be involved in maintaining lysosomal pH .The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons .The presence of conserved gating glutamate residues is typical for family members that function as antiporters.

Purification and Purity: The antibody was purified by immunogen affinity chromatography.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of CLCN7 protein.

Extra Notes: Western blot analysis of CLCN7 expression in HEK293T (A), MCF7 (B) whole cell lysates.

Bioworld Molecular Weight: ~ 110 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: H(+)/Cl(-) exchange transporter 7; Chloride channel 7 alpha subunit; Chloride channel protein 7; ClC-7

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CLCN7. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified