CLDN4 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A12912-20, A12912-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human
Protein Weight: 22kDa
Observed Molecular Weight: 18kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 1364
SWISS: O14493
Alternate Names: CPER; CPE-R; CPETR; CPETR1; WBSCR8; hCPE-R; CLDN4
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:2000 - 1:4000 IHC-P, 1:50 - 1:100 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cell Adhesion, Tight Junctions, Cytoskeleton.
NCBI Alias: CLDN4
Research Use Only