CLDND1 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-14011-60, E-AB-14011-120, E-AB-14011-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: CLDND1
Target Synonym: C3orf4; Chromosome 3 open reading frame 4; Claudin domain containing 1; Claudin domain containing 1 protein; GENX 3745; Membrane protein GENX3745; MGC111162; MGC3316; MGC9861; OTTHUMP00000217407; OTTHUMP00000217408; OTTHUMP00000217423; OTTHUMP00000217424; OTTHUMP00000217562; OTTHUMP00000217563; OTTHUMP00000217584; OTTHUMP00000217585; OTTHUMP00000217586; OTTHUMP00000217587; OTTHUMP00000217609; OTTHUMP00000217610; OTTHUMP00000217611; OTTHUMP00000217622; OTTHUMP00000217623; OTTHUMP00000217625; OTTHUMP00000217627; OTTHUMP00000217628; OTTHUMP00000217638
Research Areas: Cell Biology, Neuroscience
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q9NY35
Background: CLDND1 (claudin domain containing 1), also known as C3orf4 or HSPC174, is a 253 amino acid multi-pass membrane protein that is expressed at high levels in adult brain and at lower levels in adult heart. Existing as two alternatively spliced isoforms, CLDND1 is encoded by a gene that maps to human chromosome 3, which houses over 1, 100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Concentration: 0.2 mg/mL
Immunogen: Recombinant protein of human CLDND1
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only