Cleaved-Aggrecan (D369) rabbit pAb - ES5012

Cleaved-Aggrecan (D369) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5012-50, ES5012-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq, Jul 2008],

Alternate Name: ACAN; AGC1; CSPG1; MSK16; Aggrecan core protein; Cartilage-specific proteoglycan core protein; CSPCP; Chondroitin sulfate proteoglycan core protein 1; Chondroitin sulfate proteoglycan 1

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human Aggrecan. AA range:320-369

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 44kD

Human Gene ID: 176

Human SWISS Prot NO: P16112

Subcellular Location: Secreted, extracellular space, extracellular matrix.

Research Use Only