Cleaved-Caspase 1 Polyclonal Antibody-BZ16404

Cleaved-Caspase 1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16404-50, BZ16404-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P29466

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB,ICC/IF,IHC-F,IHC-P,ELISA

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000

Background: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Cleaved-Caspase 1 in NIH3T3Lysates using Cleaved-Caspase 1 antibody.

Bioworld Molecular Weight: Calculated MW: 45 kDa; Observed MW: 25 kDa

Specificity: IgG

Alternative Name: CASP1; IL1BC; IL1BCE; Caspase-1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45

Immunogen: The antiserum was produced against synthesized peptide derived from human Cleaved-Caspase 1. AA range:161-210

Conjugate: Unconjugated

Modification: Cleaved