Product Description

Cleaved-Caspase 3 p17 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16278-50, BZ16278-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P42574

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB,

All Applications: WB: 1/500-1/1000

Background: Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 32 kDa; Observed MW: 35 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Cleaved-Caspase3 in Jurkat and 3T3 lysates using Cleaved-Caspase3 p17 antibody., Western blot analysis of Cleaved-Caspase 3 p17 in Jurkat cells, untreated or treated with Staurosporine , using Cleaved-Caspase3 p17 antibody or βActin antibody.

Alternative Name: CASP3; CPP32; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1

Immunogen: Purified recombinant human Caspase-3 protein fragments expressed in E.coli.

Conjugate: Unconjugated

Modification: Cleaved