Cleaved-Cathepsin D HC (L169) Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA23473-50, RA23473-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: cathepsin D (CTSD) Homo sapiens This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015], Reactivity: Human, Rat, Mouse Host: Rabbit Applications: WB, ELISA Alternate Names: CTSD, CPSD, Cathepsin D Clonality: Polyclonal Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. Molecular Weight: 27 Protein Molecular Weight (kDa): 27 Storage: -20°C/1 year Human Gene ID: 1509 Human SwissProt Number: P07339 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only