Cleaved-CD97α (L530) rabbit pAb - ES8096

Cleaved-CD97α (L530) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8096-50, ES8096-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 1

Alternate Name: CD97; CD97 antigen; Leukocyte antigen CD97; CD antigen CD97

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human CD97alpha. AA range:481-530

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 55kD

Human Gene ID: 976

Human SWISS Prot NO: P48960

Subcellular Location: Cell membrane; Multi-pass membrane protein.; [Adhesion G protein-coupled receptor E5 subunit alpha]: Secreted, extracellular space.

Research Use Only