Cleaved-Kininogen-1 HC (K380) rabbit pAb - ES6027

Cleaved-Kininogen-1 HC (K380) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6027-50, ES6027-100

Citations, Manuals and MSDS Available upon request.

Background: This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2014],

Alternate Name: KNG1; BDK; KNG; Kininogen-1; Alpha-2-thiol proteinase inhibitor; Fitzgerald factor; High molecular weight kininogen; HMWK; Williams-Fitzgerald-Flaujeac factor

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from Cleaved-Kininogen-1 HC (K380) . at AA range: 300-380

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 41kD

Human Gene ID: 3827

Human SWISS Prot NO: P01042

Subcellular Location: Secreted, extracellular space.

Research Use Only