Cleaved-MMP-15 (Y132) rabbit pAb - ES1045

Cleaved-MMP-15 (Y132) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES1045-50, ES1045-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein may play a role in cancer progression. [provided by RefSeq, Jan 2016],

Alternate Name: MMP15; Matrix metalloproteinase-15; MMP-15; Membrane-type matrix metalloproteinase 2; MT-MMP 2; MTMMP2; Membrane-type-2 matrix metalloproteinase; MT2-MMP; MT2MMP; SMCP-2

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Monkey

Immunogen: The antiserum was produced against synthesized peptide derived from human MMP15. AA range:113-162

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 61kD

Human Gene ID: 4324

Human SWISS Prot NO: P51511

Subcellular Location: Membrane; Single-pass type I membrane protein; Extracellular side.

Research Use Only