Cleaved PARP Monoclonal Antibody (M4) - RA10593

Cleaved PARP Monoclonal Antibody (M4)

Size: 50μL, 100μL

Catalogue Numbers: RA10593-50, RA10593-100

Citations, Manuals and MSDS Available upon request.

Background: poly (ADP-ribose) polymerase 1 (PARP1) Homo sapiens This gene encodes a chromatin-associated enzyme, poly (ADP-ribosyl) transferase, which modifies various nuclear proteins by poly (ADP-ribosyl) ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008],

Condition: PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Storage Instructions: -20°C/1 year

Applications: WB

Species Cross-Reactivity: Human

GeneID (Human): 142

Protein MW (KDa): 116,89

SWISS: P09874

Source: Mouse

Research Use Only