Product Description

Cleaved PARP Monoclonal Antibody (Mix)

Sizes: 50μL, 100μL

Catalogue Numbers: RA10574-50, RA10574-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: poly (ADP-ribose) polymerase 1 (PARP1) Homo sapiens This gene encodes a chromatin-associated enzyme, poly (ADP-ribosyl)transferase, which modifies various nuclear proteins by poly (ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008],

Reactivity: Human

Host: Mouse

Applications: IF/ICC, WB, IHC-p,

Alternate Names: PARP1, ADPRT, PPOL, Poly [ADP-ribose] polymerase 1, PARP-1, ADP-ribosyltransferase diphtheria toxin-like 1, ARTD1, NAD(+) ADP-ribosyltransferase 1, ADPRT 1, Poly[ADP-ribose] synthase 1

Clonality: Monoclonal

Dilution: IF: 1:50-200 WB: 1:2000-5000 IHC 1:50-300

Storage: -20°C/1 year

Condition: PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Human Gene ID: 142

Protein Molecular Weight（KDa): 116, 89

Molecular Weight: 116, 89

Research Use Only