Cleaved-PARP1 Monoclonal Antibody-MB10743

Cleaved-PARP1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10743-50, MB10743-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P09874

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB: 1/500-1/1000

Background: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Cleaved- PARP1 in K562Lysates using Cleaved-PARP1 antibody.

Bioworld Molecular Weight: Calculated MW: 113 kDa; Observed MW: 89 kDa

Specificity: IgG

Alternative Name: PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1

Immunogen: A synthetic peptide of human Cleaved PARP1

Conjugate: Unconjugated

Modification: Cleaved