Cleaved-Plasma Kallikrein HC (R390) Polyclonal Antibody - BT-AP01961

Cleaved-Plasma Kallikrein HC (R390) Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP01961-20, BT-AP01961-50, BT-AP01961-100

Citations, Manuals and MSDS Available upon request.

Background: KLKB1 encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in KLKB1 cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Areas: Cell Biology

Target Protein: KLKB1

Applications: WB, IHC-p, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Cleaved-Plasma Kallikrein HC (R390) Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 71370

UniProt Accession: Human: P03952; Mouse: P26262

Synonyms: KLKB1; KLK3; Plasma kallikrein; Fletcher factor; Kininogenin; Plasma prekallikrein

GeneID: Human: 3818

Research Use Only