Cleaved-Thrombin APII (R327) Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA23526-50, RA23526-100
Citations, Manuals and MSDS Available upon request.
Background: coagulation factor II, thrombin (F2) Homo sapiens Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Alternative Names: F2; Prothrombin; Coagulation factor II
Applications: WB; ELISA
Species Cross-Reactivity: Human; Rat; Mouse
GeneID (Human): 2147
Protein MW (KDa): 19
SWISS: P00734
Source: Rabbit
Research Use Only