Cleaved-Thrombin APII (R327) rabbit pAb - ES1055

Cleaved-Thrombin APII (R327) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES1055-50, ES1055-100

Citations, Manuals and MSDS Available upon request.

Background: Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015],

Alternate Name: F2; Prothrombin; Coagulation factor II

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human THRB. AA range:278-327

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 19kD

Human Gene ID: 2147

Human SWISS Prot NO: P00734

Subcellular Location: Secreted, extracellular space.

Research Use Only