Product Description

CLIC4 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10744-50, MB10744-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q9Y696

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-F, IHC-P, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background: Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis).

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 29 kDa; Observed MW: 29 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of CLIC4 in rat Brain, C6, 3T3, Hela lysates using CLIC4 antibody., Immunocytochemistry analysis of CLIC4 in Hela using CLIC4 antibody, and DAPI, Immunohistochemistry analysis of paraffin-embedded Human Cholangiocarcinoma using CLIC4 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: CLIC4; Chloride intracellular channel protein 4; Intracellular chloride ion channel protein p64H1

Immunogen: A synthetic peptide of human CLIC4

Conjugate: Unconjugated

Modification: Unmodified