Product Description

CLIP2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61639-50, BS61639-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Williams Syndrome (WS) is a developmental disorder characterized by cardiovascμlar problems, dysmorphic features, mental retardation or learning difficμlties and several typical behavioral and neurological abnormalities. In Williams Syndrome patients, a heterozygous deletion is present in a region on chromosome 7q11.23 (the Williams Syndrome critical region), which spans approximately 20 genes. This region comprises the CYLN2 gene, which encodes the cytoplasmic linker protein of (CLIP-115). CLIP-115 is a microtubμle-binding protein that is abundantly expressed in the brain. Mice with haploinsufficiency for the CYLN2 gene have features similar to that of WS, including mild growth deficiency, brain abnormalities, hippocampal dysfunction and particμlar deficits in motor coordination.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: CAP-Gly domain-containing linker protein 2, Cytoplasmic linker protein 115, CLIP-115, Cytoplasmic linker protein 2, Williams-Beuren syndrome chromosomal region 3 protein, Williams-Beuren syndrome chromosomal region 4 protein, CLIP2, CYLN2, KIAA0291, WBSCR3, WBSCR4, WSCR4

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding Human CLIP2.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CLIP2 polyclonal antibody detects endogenous levels of CLIP2 protein.

Molecular Weight: ~ 115 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9UDT6

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only