CLK1 Polyclonal Antibody - BT-AP01980

CLK1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP01980-20, BT-AP01980-50, BT-AP01980-100

Citations, Manuals and MSDS Available upon request.

Background: CLK1 encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein (CDC like kinase 1) phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for CLK1.

Research Areas: Signal Transduction

Target Protein: CLK1

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: CLK1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 57205

UniProt Accession: Human: P49759; Mouse: P22518

Synonyms: CLK1; CLK; Dual specificity protein kinase CLK1; CDC-like kinase 1

GeneID: Human: 1195; Mouse: 12747

Research Use Only