CLN5 rabbit pAb - ES4682

CLN5 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4682-50, ES4682-100

Citations, Manuals and MSDS Available upon request.

Background: ceroid-lipofuscinosis, neuronal 5 (CLN5) Homo sapiens This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.[provided by RefSeq, Oct 2008],

Alternate Name: CLN5; Ceroid-lipofuscinosis neuronal protein 5; Protein CLN5

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human CLN5. AA range:171-220

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 48kD

Human Gene ID: 1203

Human SWISS Prot NO: O75503

Subcellular Location: [Ceroid-lipofuscinosis neuronal protein 5, secreted form]: Lysosome.; [Ceroid-lipofuscinosis neuronal protein 5]: Membrane; Single-pass type II membrane protein. An amphipathic anchor region facilitates its association with the membrane.

Research Use Only