CLN6 rabbit pAb - ES6687

CLN6 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6687-50, ES6687-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function. [provided by RefSeq, Oct 2008],

Alternate Name: CLN6; Ceroid-lipofuscinosis neuronal protein 6; Protein CLN6

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human CLN6. AA range:221-270

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 40kD

Human Gene ID: 54982

Human SWISS Prot NO: Q9NWW5

Subcellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum.

Research Use Only