Product Description

CLTCL1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90311-50, BS90311-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P53675(Human) Q68FD5(Mouse) P11442(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB:1:500-1:2,000
IHC:1:50-1:200

Background: Clathrin is a major cytosolic coat protein in pits and vesicles originating from the plasma membrane and the trans-Golgi network. In receptor-mediated endocytosis, receptor proteins are englufed by clathrin-coated vesicles. Clathrin is composed of three heavy chains and three light chains which associate non-covalently to form a triskelion structure. Clathrin heavy chain (HC) is composed of a terminal globular domain, a distal segment and a proximal segment containing a light chain binding site. The proximal segment of the Clathrin HC protein is essential for interactions between clathrin heavy chains and light chains which result in the formation of the triskelion structure.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: CLTCL1 polyclonal antibody detects endogenous levels of CLTCL1 protein.

Bioworld Molecular Weight: 191/187 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Clathrin heavy chain on Hela (1) and PC-12 (2) cell lysate using anti-Clathrin heavy chain antibody at 1/1,000 dilution., Immunohistochemical analysis of paraffin-embedded human adrenal gland tissue using anti-Clathrin heavy chain antibody. Counter stained with hematoxylin.

Alternative Name: CLH-22, CLTCL1, CLH22, CLTCL, CLTD, CHC17, Clathrin heavy chain, Clathrin heavy chain 1, Clathrin heavy chain 2, Clathrin heavy chain like 1, Clathrin heavy chain on chromosome 17, Clathrin heavy polypeptide, CLH 17, CLH 22, CLH-17, CLH1, CLH17, CLH22, CLTC, CLTCL, CLTCL1, CLTCL2, CLTD, Hc, KIAA0034,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified