Product Description

CNGB1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16433-50, BZ16433-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: Q14028

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ELISA

All Applications: WB: 1/500-1/1000 ELISA: 1/10000

Background: Subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP.Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties: it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 140 kDa; Observed MW: 102 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of CNGB1 in various lysates using CNGB1 antibody., Western blot analysis of CNGB1 in 3T3 lysates using CNG1β antibody., Western blot analysis of CNGB1 in NIH/3T3 and A549 lysates using CNGB1 antibody. The Lane on the right is blocked with the synthesized peptide.

Alternative Name: CNG4; GAR1; GARP; RP45; CNCG2; CNCG4; GARP2; RCNC2; RCNCb; CNCG3L; CNGB1B; RCNCbeta

Immunogen: The antiserum was produced against synthesized peptide derived from human CNGB1. AA range:571-620

Conjugate: Unconjugated

Modification: Unmodified