Product Description

CNOT2(Phospho-Ser101)Polyclonal Antibody

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Sizes: 50µl, 100µl

Catalogue Numbers: BS65143-50, BS65143-100

Swiss-Prot: Q9NZN8

Host: Rabbit

CNOT2(Phospho-Ser101)Polyclonal Antibody-BS65143

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: IHC-P, IF (paraffin section), ELISA

All Applications: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Background: CCR4-NOT transcription complex subunit 2(CNOT2) Homo sapiens This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010],

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity: Phospho-CNOT2 (S101) Polyclonal Antibody detects endogenous levels of CNOT2 protein only when phosphorylated at S101.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry analysis of paraffin-embedded human brain, using CNOT2 (Phospho-Ser101) Antibody. The picture on the right is blocked with the phospho peptide., Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using CNOT2 (Phospho-Ser101) Antibody

Alternative Name: CNOT2; CDC36; NOT2; HSPC131; MSTP046; CCR4-NOT transcription complex subunit 2; CCR4-associated factor 2

Immunogen: The antiserum was produced against synthesized peptide derived from human CNOT2 around the phosphorylation site of Ser101. AA range:67-116

Modification: Phosphorylation

Conjugate: Unconjugated