Product Description

CNOT7 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16995-50, BZ16995-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q60809

Host: Rabbit

Reactivity: Human, Mouse, Rat, Monkey

Applications: WB, IHC-P, FC, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20 FC: 1/50-1/100

Background: Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 33 kDa; Observed MW: 33 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of CNOT7 in F9, C6, PC-12, 3T3, Raw264.7 lysates using CNOT7 antibody., Western blot analysis of CNOT7 in Molt4, Raji, COS7, Hela lysates using CNOT7 antibody., Immunohistochemistry analysis of paraffin-embedded Human lung cancer using CNOT7 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: CCR4-associated factor 1; CAF-1

Immunogen: A synthetic peptide of mouse CNOT7

Conjugate: Unconjugated

Modification: Unmodified