CNPase Polyclonal Antibody-BS90315

CNPase Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90315-50, BS90315-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P09543(Human) P16330(Mouse) P13233(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC IHC FC

All Applications: WB:1:1,000-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Background: 2',3'-cyclic nucleotide-3'-phosphodiesterase (CNPase) is a membrane-bound enzyme that can link tubulin to membranes and may regulate cytoplasmic microtubule distribution. CNPase acts as a microtubule-associated protein by promoting microtubule assembly; this activity resides in the C-terminus of the enzyme. CNPase is firmly associated with tubulin from brain tissue and thyroid cells and can be found at high concentrations in central nervous system myelin and in the outer segments of photoreceptors in the retina. Acute lead intoxication leads to disturbances in CNPase activity and the morphology of myelin.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: CNPase polyclonal antibody detects endogenous levels of CNPase protein.

Bioworld Molecular Weight: 48 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of CNPase on mouse brain lysates using anti-CNPase antibody at 1/1,000 dilution., ICC staining CNPase in SHG-44 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Alternative Name: CNP, CNPase, 2'', 2'3' cyclic nucleotide 3' phosphodiesterase, 3''-cyclic-nucleotide 3''-phosphodiesterase, CN37, CNP 1, CNP, CNP1, CNPase,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified