Product Description

COL11A2 (P1232) Polyclonal Antibody

Catalogue Numbers:BS9132-50, BS9132-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P13942

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC

All Applications: WB: 1:500~1:1000
IHC: 1:50~1:200

Background: COL11A2 (collagen, type XI, alpha 2), also known as Collagen α2 Type XI, HKE5, PARP, STL3, DFNA13 or DFNB53, is a 1,736 amino acid secreted protein that contains one TSP N-terminal domain and is thought to play an essential role in fibrillogenesis, specifically by controlling the lateral growth of collagen fibrils. Defects in the gene encoding COL11A2 are the cause of Stickler syndrome type 3 (STL3), autosomal recessive otospondylomegaepiphyseal dysplasia (OSMED), Weissenbacher-Zweymueller syndrome (WZS) and non-syndromic sensorineural deafness autosomal dominant type 13 (DFNA13). Eight isoforms of COL11A2 exist due to alternative splicing events.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Bioworld Molecular Weight: ~ 172 kDa

Specificity: COL11A2 (P1232) polyclonal antibody detects endogenous levels of COL11A2 protein.

Note: For research use only, not for use in diagnostic procedure.
Alternative Name: COL11A2; Collagen alpha 2(XI); Collagen alpha-2(XI) chain; Collagen type XI alpha 2; DAQB-79P13.8; DFNA13; HGNC:2187; HKE5; PARP; STL3;

Immunogen: Synthetic peptide, corresponding to amino acids 1200-1250 of Human COL11A2.

Conjugate: Unconjugated

Modification: Unmodified