COL19A1 (Y442) Polyclonal Antibody-BS9133

COL19A1 (Y442) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS9133-50, BS9133-100

Sizes: 50µl, 100µl

Swiss-Prot: Q14993

Host: Rabbit

Reactivity: Human

Applications: IHC

Background: Collagen Type XIX is an 1,142 amino acid protein encoded by the human gene COL19A1. Collagen Type XIX belongs to the fibril-associated collagens with interrupted helices (FACIT) family. Collagen Type XIX is thought to act as a cross-bridge between collagen fibrils and other extracellular matrix molecules. Collagen Type XIX is also believed to be involved in skeletal myogenesis in the developing esophagus. It may also play a role in organization of the pericellular matrix or the sphinteric smooth muscle. Collagen Type XIX is normally found as an oligomer, the subunits being disulfide-linked. Expression of Collagen Type XIX is mainly localized to vascular, neuronal, mesenchymal, and some epithelial basement membrane zones in umbilical cord.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: COL19A1 (Y442) polyclonal antibody detects endogenous levels of COL19A1 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of COL19A1 (Y442) pAb in paraffin-embedded human breast carcinoma tissue at 1:50,showing nucleus staining.Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.

Bioworld Molecular Weight: ~ 115 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Collagen alpha-1(XIX) chain; Collagen alpha-1(Y) chain; COL19A1

Immunogen: Synthetic peptide, corresponding to amino acids 411-464of Human COL19A1.

Conjugate: Unconjugated

Modification: Unmodified