Product Description

COL2A1 Monoclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-70295-60, E-AB-70295-120, E-AB-70295-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: COL2A1

Target Synonym: Alpha 1 type II collagen; Alpha-1 type II collagen; AOM; Cartilage collagen; Chondrocalcin; CO2A1; COL11A3; Col2a1; Collagen II alpha 1 polypeptide; SEDC

Research Areas: Cancer, Signal Transduction, Stem Cells

Conjugation: Unconjugated

Host: Mouse

Species Reactivity: Mouse, Rat

Application: IHC

Isotype: IgG

Clonality: Monoclonal

Clone No.: 2F12D3

UNIProt ID: P28481

Background: This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.

Concentration: 2.6 mg/mL

Immunogen: Recombinant protein corresponding to Mouse collagen II

Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: IHC 1:300-1:1000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only