COL2A1 Polyclonal Antibody - BT-AP02080

COL2A1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP02080-20, BT-AP02080-50, BT-AP02080-100

Citations, Manuals and MSDS Available upon request.

Background: COL2A1 encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in COL2A1 are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for COL2A1.

Research Areas: Signal Transduction

Target Protein: COL2A1

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: COL2A1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 141785

UniProt Accession: Human: P02458; Mouse: P28481; Rat: P05539

Synonyms: COL2A1; Collagen alpha-1(II) chain; Alpha-1 type II collagen

GeneID: Human: 1280; Mouse: 12824; Rat: 25412

Research Use Only