Product Description

COL5A1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP02088-20, BT-AP02088-50, BT-AP02088-100

Citations, Manuals and MSDS Available upon request.

Background: COL5A1 encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. The encoded procollagen protein occurs commonly as the heterotrimer pro-alpha1 (V)-pro-alpha1 (V)-pro-alpha2 (V). Mutations in COL5A1 are associated with Ehlers-Danlos syndrome, types I and II. Alternative splicing of COL5A1 results in multiple transcript variants.

Research Areas: Signal Transduction

Target Protein: COL5A1

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: COL5A1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 183560

UniProt Accession: Human: P20908; Mouse: O88207

Synonyms: COL5A1; Collagen alpha-1(V) chain

GeneID: Human: 1289

Research Use Only