Product Description

COL6A2 (Y711) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS2181-50, BS2181-100

Sizes: 50µl, 100µl

Swiss-Prot: P12110

Host: Rabbit

Reactivity: Human

Applications: WB, IHC

Background: Collagens (COLs) are fibrous, extracellular matrix proteins with high tensile strength that function as the major components of connective tissue, such as tendons and cartilage. All COL proteins contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Existing as a trimer with two other type VI alpha proteins, COL6A2 acts as a cell-binding protein that plays an important role in the organization of matrix components. Defects in the gene encoding COL6A2 are associated with Bethlem myopathy (BM) and Ullrich congenital muscular dystrophy (UCMD). Multiple isoforms of COL6A2 exist due to alternative splicing events.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: COL6A2 (Y711) polyclonal antibody detects endogenous levels of COL6A2 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of COL6A2 (Y711) pAb at 1:1000 dilution
Lane 1: U-87MG whole cell lysate (40ug)
Lane 2: PC3 whole cell lysate (40ug)
Lane 3: MCF-7 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of COL6A2 (Y711) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

Bioworld Molecular Weight: ~109 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Collagen alpha 2(VI) chain; Collagen alpha-2(VI) chain; Collagen VI alpha 2 polypeptide; PP3610;

Immunogen: Synthetic peptide, corresponding to amino acids 681-730 of Human COL6A2.

Conjugate: Unconjugated

Modification: Unmodified