COL7A1 Polyclonal Antibody - BT-AP02095

COL7A1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP02095-20, BT-AP02095-50, BT-AP02095-100

Citations, Manuals and MSDS Available upon request.

Background: COL7A1 encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen.

Research Areas: Signal Transduction

Target Protein: COL7A1

Applications: IHC-p, IF, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: COL7A1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 295220

UniProt Accession: Human: Q02388; Mouse: Q63870

Synonyms: COL7A1; Collagen alpha-1(VII) chain; Long-chain collagen; LC collagen

GeneID: Human: 1294; Mouse: 12836

Research Use Only