COL7A1 rabbit pAb - ES4749

COL7A1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4749-50, ES4749-100

Citations, Manuals and MSDS Available upon request.

Background: collagen type VII alpha 1 chain (COL7A1) Homo sapiens This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. [provided by RefSeq, Jul 2008],

Alternate Name: COL7A1; Collagen alpha-1 (VII) chain; Long-chain collagen; LC collagen

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human Collagen VII alpha1. AA range:1841-1890

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 1294

Human SWISS Prot NO: Q02388

Subcellular Location: Secreted, extracellular space, extracellular matrix, basement membrane.

Research Use Only