COL9A1 rabbit pAb - ES4750

COL9A1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4750-50, ES4750-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],

Alternate Name: COL9A1; Collagen alpha-1 (IX) chain

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from COL9A1 . at AA range: 390-470

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 120kD

Human Gene ID: 1297

Human SWISS Prot NO: P20849

Subcellular Location: Secreted, extracellular space, extracellular matrix.

Research Use Only