Collagen II mouse Monoclonal Antibody (8F6) - BT-MCA0357

Collagen II mouse Monoclonal Antibody (8F6)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA0357-20, BT-MCA0357-50, BT-MCA0357-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.

Research Areas: Signal transduction; Stem cells

Target Protein: COL2A1

Applications: IHC-p, IF

Reactivity: Human,Mouse,Rat

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Collagen alpha-1(II) chain

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P02458; Mouse: P28481; Rat: P05539

Synonyms: Collagen alpha-1(II) chain; Alpha-1 type II collagen

GeneID: Human: 1280

Research Use Only