Product Description

Connexin-26 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA23679-50, RA23679-100

Citations, Manuals and MSDS Available upon request.

Background: gap junction protein beta 2 (GJB2) Homo sapiens This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness. [provided by RefSeq, Oct 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: IHC 1:100-200

Alternative Names: GJB2; Gap junction beta-2 protein; Connexin-26; Cx26; YM3545

Applications: IHC-p; IF (paraffin section)

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 2706

Protein MW (KDa): 26

SWISS: P29033

Source: Rabbit

Research Use Only