Connexin-26 rabbit pAb - ES2029

Connexin-26 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2029-50, ES2029-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness. [provided by RefSeq, Oct 2008],

Alternate Name: GJB2; Gap junction beta-2 protein; Connexin-26; Cx26

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human Connexin-26. AA range:45-94

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 26kD

Human Gene ID: 2706

Human SWISS Prot NO: P29033

Subcellular Location: Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Colocalizes with GJB4 at gap junction plaques in the cochlea.

Research Use Only