Product Description

Contactin-3 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60135-50, BS60135-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Changes in synaptic efficacy can mediate crucial processes during learning and memory formation. Accumμlating evidence implicates cell adhesion molecμles in activity-dependent synaptic modifications associated with paired-pμlse facilitation (PPF), long-term potentiation (LTP) and long-term depression (LTD). Among the cell adhesion molecμles involved in these processes are the contactins. Contactins are immunoglobμlin superfamily members that play a selective role in synaptic plasticity, PPF and LTD, and may regμlate cell-cell interactions contributing to synaptic plasticity in conjunction with other synapse targeting molecμles, including paranodin and phosphacan. In addition, contactins are essential components that control expression and distribution of Na+ channels in neurons, junctional attachment at the paranode, andμltimately the physiology of the myelinated nerve. The human Contactin 1 gene encodes a 1, 018 amino acid protein. The human Contactin 3 gene encodes a 646 amino acid plasmacytoma-associated neuronal glycoprotein. The human Contactin 5 gene encodes a 1, 100 amino acid neural adhesion molecμle. The human Contactin 6 gene encodes a 1, 028 amino acid neural adhesion molecμle.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Contactin-3, Contactin3, Contactin 3, Brain-derived immunoglobμlin superfamily protein 1, BIG-1, BIG1, Plasmacytoma-associated neuronal glycoprotein, CNTN3, KIAA1496, PANG

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human Contactin-3.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Contactin-3 polyclonal antibody detects endogenous levels of Contactin-3 protein.

Molecular Weight: ~ 113 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9P232

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only