Product Description

COVID-19 Nucleocapsid Protein Polyclonal Antibody

Catalogue Numbers: BS67276-50, BS67276-100

Sizes: 50µl, 100µl

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: P0DTC9

Host: Rabbit

Reactivity: COVID-19

Applications: ELISA, WB

All Applications: WB (1/1000 - 1/3000), ELISA: Use at an assay dependent dilution

Background: The cause of the COVID-19 pandemic is a novel and highly pathogenic coronavirus, termed SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2). SARS-CoV-2 is a member of the Coronaviridae family of viruses. The genome of SARS-CoV-2 is relatively large and encodes up to 29 open reading frames (ORFs). These include ORF1a and ORF1b (further processed into 16 non-structural proteins), 9 accessory proteins, and 4 canonical structural proteins: spike (S), envelope (E), membrane (M), and nucleocapsid (N). The nucleocapsid (N) protein is a phosphoprotein that plays a critical role in viral assembly. It binds to the viral genomic RNA, enabling its packaging into the ribonucleoprotein complex (RNP), and is the most abundant protein in the virion. Evidence from studies in SARS-CoV-2 and other coronaviruses suggest functions for nucleocapsid (N) protein beyond viral RNA packaging, including roles in viral replication and suppressing host immune responses to viral infection.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes COVID-19 Nucleocapsid Protein.

Extra Notes: Western blot analysis of COVID-19 Nucleocapsid Protein using Recombinant COVID-19 Nucleocapsid Protein (A).

Bioworld Molecular Weight: ~ 55 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Nucleoprotein; Nucleocapsid protein; NC; Protein N

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of COVID-19 Nucleocapsid Protein. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified