COX IV Monoclonal Antibody (6C8), AbFluor™ 680 Conjugated Sizes: 50μL, 100μL Catalogue Numbers: RA11005-50, RA11005-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: cytochrome c oxidase subunit 4I1 (COX4I1) Homo sapiens Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes Reactivity: Human, Rat, Mouse Host: Mouse Applications: WB, IHC-p, IF/ICC, Alternate Names: COX4I1 Clonality: Monoclonal Dilution: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300, IF 1:200 . Storage: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. Store in dark. Condition: Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol. Human Gene ID: 1327 Research Use Only