COX IV Monoclonal Antibody (6C8) - BT-MCA0026

COX IV Monoclonal Antibody (6C8)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA0026-20, BT-MCA0026-50, BT-MCA0026-100

Citations, Manuals and MSDS Available upon request.

Background: Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes

Research Areas: Signal transduction; Cancer; Metabolism; Tags and; cell markers

Target Protein: COX4I1

Applications: WB, IHC-p, IF, ICC

Reactivity: Human,Rat,Mouse

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 19577

UniProt Accession: Human: P13073; Mouse: P19783; Rat: P10888

Synonyms: COX4I1; COX4; Cytochrome c oxidase subunit 4 isoform 1; mitochondrial; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1

GeneID: Human: 1327; Mouse: 12857; Rat: 29445

Research Use Only